Eshuis G, Hock J, du Sarvaas GM, et al. - This research sought to provide a perspective for the interpretation of exercise capacity (peakVO ₂ ) in patients with repaired Tetralogy of Fallot (patients with rTOF) by describing the course of peakVO ₂ from patients aged 6–63 years. Researchers conducted a retrospective study between September 2001 and December 2016 in the German Heart Centre Munich, Germany, and in the University Medical Centre Groningen, the Netherlands. They collected a total of 1,175 cardiopulmonary exercise tests from 586 patients with rTOF, 46% female. This research gives a context for peakVO ₂ across ages in patients with rTOF under contemporary treatment strategies. It demonstrated that the reduction in peakVO ₂ originates from childhood and declines over time. In patients with rTOF, gender differences were similar to natural existing sex differences.