Excess risk for atherosclerotic cardiovascular outcomes among US adults with HIV in the current era
Journal of the American Heart Association Jan 10, 2020
Rosenson RS, Hubbard D, Monda KL, et al. - Researchers compared US adults aged ≥ 19 years with and without HIV who had commercial or supplemental Medicare health insurance between January 1, 2011, and December 31, 2016, with respect to the risk for atherosclerotic cardiovascular disease (ASCVD) events between these populations. They frequency-matched (1:4) 82,426 beneficiaries with HIV to 329,704 without HIV on age, gender, and calendar year. Participants were observed over a median duration of 1.6 years (maximum, 6 years). Among beneficiaries with and without HIV, the estimated rate per 1000 person-years was 5.53 and 3.49 for ASCVD, respectively. This value was estimated to be 3.58 and 2.34 for myocardial infarction, 1.49 and 0.94 for stroke, and 0.65 and 0.31 for lower extremity artery disease hospitalizations, respectively, for beneficiaries with and without HIV. Overall, a higher ASCVD risk was observed in adults with HIV in the United States vs their counterparts without HIV.
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