Csorba A, Maka E, Maneschg OA, et al. - In this cross-sectional study involving three children and three adults who had nephropathic cystinosis [a rare autosomal recessive storage disease] and corneal cystine depositions, researchers sought to analyze the features of crystal arrangement in different corneal layers and the assessment of corneal morphological changes with age. In vivo confocal microscopy and anterior segment optical coherence tomography verified an age-related pattern of crystal deposition. Crystals tend to locate anteriorly in children, whereas deposits are found posteriorly in the corneal stroma in adults.