Mannino DM, et al. - Given the recovery patterns from acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in newly diagnosed or maintenance treatment-naïve patients with COPD are not fully known, researchers describe the course of AECOPD in these patients at the time of treatment for the symptoms of acute respiratory tract infection (RTI). In this secondary analysis of TICARI 1 trial, they found that after clinic visit for AECOPD with symptoms of RTI, relapse or persistent symptoms were experienced by a substantial portion of newly diagnosed or maintenance treatment-naïve patients with COPD.