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Evolution of isolated systolic hypertension with normal central blood pressure in adolescents-Prospective study

Pediatric Nephrology Jan 22, 2021

Obrycki Ł, Feber J, Brzezińska G, et al. - Researchers conducted this prospective study to examine changes in office, ambulatory blood pressure (ABPM), central systolic blood pressure (cSBP), hemodynamic parameters, and target organ damage (TOD) over a 1-year follow-up in a group of non-obese children with spurious hypertension (sHT). One hundred thirty-eight patients (31 girls; 22%) of the 294 patients referred for primary hypertension had ABPM-confirmed hypertension. Data reported that 23% of adolescents with sHT developed sustained hypertension after 1 year of non-pharmacological treatment, with the change in serum uric acid being the key indicator of the change in cSBP.

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