Forestier A, Le Gouellec N, Behal H, et al. - This study was attempted to describe the evolution of interstitial lung disease (ILD) extent on HRCT scan in systemic sclerosis (SSc), to distinguish baseline prognostic factors correlated with ILD evolution, and to evaluate if the evolution of pulmonary function tests (PFTs) correlated with this evolution. Researchers included 58 SSc with ILD (SSc-ILD) patients. They collected all HRCT scans and PFTs available. The linear mixed model with random effect was applied to modelize PFTs and HRCT scans evolution. It was shown that the male gender, dcSSc, anti-topoisomerase 1 antibodies, and a less severe ILD at baseline was correlated with a faster progression of ILD over time. The findings revealed that the evolution of DLCO significantly associated with a change in ILD extent on HRCT scan. This research guides defining the profile of individuals at risk of experiencing a progression of ILD on HRCT scans.