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Evaluation of tranexamic acid in trauma patients: A retrospective quantitative analysis

The American Journal of Emergency Medicine Jun 12, 2018

Ng M, et al. - Researchers used the British Columbia Trauma Registry to determine the use and appropriateness of tranexamic acid (TXA) in trauma patients that presented to the Emergency Department at Royal Columbian Hospital (RCH) between April 2012 to June 2015 and met the indications for TXA. In this retrospective chart review, the percentage that met indications for TXA, received TXA according to the CRASH-2 protocol, received a pre-hospital dose, and received TXA ≤1, >1 to ≤3, or >3 h from injury were the primary outcomes. They found that TXA was received according to the CRASH-2 protocol by <10% of adult trauma patients that met the indication for TXA. Data also showed that 76% of those patients that received TXA, did so within 3 h.
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