Sok P, Mgbere O, Pompeii L, et al. - This research sought to ascertain the prevalence and influence of sociodemographic, behavioral, and clinical factors on complete antiretroviral therapy (ART) adherence among people living with HIV (PLWH) receiving medical care in Houston/Harris County, Texas. Between 2009 to 2014, data from the Houston Medical Monitoring Project survey collected among 1,073 participants were used in this study. Researchers employed Rao–Scott Chi-square test and multivariable proportional-odds cumulative logit regression models to distinguish the sociodemographic, behavioral, and clinical characteristics of complete combined adherence among the three groups of PLWH living with HIV infection. The results demonstrate that measures of adherence should include all adherence types (dose, schedule, instruction), as utilizing a single adherence type will overestimate adherence level in PLWH receiving medical care. According to the findings, intervention efforts to maintain adherence should target recently infected PLWH, while those intended at improving adherence should focus on longer infected PLWH.