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Evaluation of intraoperative slow-release dexamethasone implant combined with idiopathic epiretinal membrane removal

Graefe's Archive for Clinical and Experimental Ophthalmology Sep 10, 2020

Savastano A, Bitossi A, Giansanti F, et al. - Researchers conducted this observational retrospective study to assess the effectiveness of intraoperative slow-release dexamethasone implant (DEX) combined with the removal of the idiopathic epiretinal membrane (ERM). Data from 40 patients with phakic eyes affected by idiopathic ERM have been analyzed. All patients had cataract phacoemulsification, 25-gauge (G) pars plana vitrectomy (PPV), ERM removal with DEX implant (“DEX YES” group, #20) or without DEX implant (“DEX NO” group, #20). In this analysis, best-corrected visual acuity (BCVA) improvement was accelerated by DEX 15 days after surgery. Central macular thickness (CMT) significantly reduced at each follow-up visit in both groups, and no statistically significant increase of IOP was identified at each follow-up visit. However, there was no evidence of further anatomical (CMT) and functional (BCVA) DEX efficacy combined with the removal of idiopathic ERM by 25-G PPV at 30 and 90 days follow-up.

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