• Profile
Close

Evaluation of interleukin 29 in autoimmune and inflammatory thyroid diseases

Clinical Endocrinology Jan 28, 2021

Falkowski B, Szczepanek‐Parulska E, Krygier A, et al. - Researchers sought to compare interleukin 29 (IL‐29) level between healthy controls (CS) and patients suffering from selected thyroid disorders: Graves’ disease (GD), Hashimoto’s thyroiditis (HT), and subacute thyroiditis (SAT). The GD subgroup vs the CS subgroup was found to have higher IL‐29 level. IL‐29 levels did not differ between the CS and HT or SAT subgroups. In multivariable linear regression analysis, IL‐29 was identified as a statistically significant independent predictor of GD presence following adjustment for TRAb. For the first time ever, increased IL‐29 serum concentrations were found in patients suffering from GD. The likely involvement of IL‐29 in one of the pathogenetic pathways of GD, but no HT and SAT, was suggested. There is a need for future investigations to assess the potential of the protein as a treatment target in GD.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay