Evaluation of dry eye subtypes and characteristics using conventional assessments and dynamic tear interferometry
British Journal of Ophthalmology Jun 12, 2021
Ji YW, Seong H, Park SY, et al. - In this investigation involving 309 patients diagnosed with dry eye (DE) and 69 healthy controls, researchers sought to assess subtypes and characteristics of DE using conventional tests and dynamic tear interferometry and to examine determinants of disease severity in each DE subtype. All eyes were assessed using Ocular Surface Disease Index, Schirmer’s test I, and Meibomian gland dysfunction grade were analyzed. Using DR-1α and LipiView II, the tear interferometric pattern and lipid layer thickness were determined, respectively. According to dynamic interferometric analysis, 56.6% of patients with DE had Jupiter patterns, indicating aqueous deficiency, while 43.4% had crystal patterns, indicating lipid deficiency. According to the findings, the majority of evaporative DE (EDE) patients have an aqueous deficiency, which can aggravate symptoms even in patients with lipid-deficient mixed-aqueous-deficient DE/EDE. To determine the best treatment for each DE patient, conventional assessments should be combined with interferometric tear analysis.
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