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Evaluation of a rapid one-step PSA test for primary prostate cancer screening

BMC Urology Oct 02, 2021

Ashida S, Yamasaki I, Kawada C, et al. - In this analysis of a one-step prostate-specific antigen (PSA) test for prostate cancer (PC) screening, the feasibility of PSA testing using the PSA SPOT test kit was evident. The test affords a useful and convenient tool for primary PC screening, with its low cost and speed.

  • A large population of men underwent PC screening using the PSA SPOT test.

  • The test afforded a sensitivity 79.9%, specificity 93.0%, positive and negative predictive values 65.4 and 96.6%, and accuracy was 91.2%.

  • With variations in the reading time, changes occurred in the sensitivity and specificity of the test.

  • Quantitative evaluation of the intensity of the band showed correlation with the PSA value.

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