Xie D, et al. - The efficacy of the Sinus and Nasal Quality of Life Survey (SN-5) underwent an inspection for the analysis of sinonasal symptoms in the pediatric cystic fibrosis (CF) cohort. A necessity persisted for a validated CRS quality of life (QOL) instrument for the study group. Despite the previous elucidation of SN-5 as a potential instrument, a greater benefit could be found in children aged 0-4 years.