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Evaluating the effect of intravenous acetaminophen in multimodal analgesia after total hip arthroplasty: A randomized controlled trial

Journal of Arthroplasty Mar 01, 2019

Takeda Y, et al. - In this single-center, prospective, open-label randomized control study, 97 individuals were estimated to evaluate the outcome of intravenous acetaminophen in multimodal analgesia after total hip arthroplasty (THA). They administered intravenous acetaminophen after surgery to study group (IA) whereas the control group was given only a standard pain control. They recorded an improvement in NRS scores IA group at rest 24 hours after THA compared to the control group indicating a positive impact of IA usage for pain relief. They noted a significantly lower value of total fentanyl citrate consumption after surgery for 24 hours in the IA group vs the control group (52.07 ± 7.64 mg vs 57.83 ± 12.44mg).
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