Chapelle T, et al. - This study was planned to test the hypothesis that a Hepatobiliary Scintigraphy (HBS^BSA) based formula was a better predictor for post-hepatectomy liver failure (PHLF) than platelet-based liver scores (PBLS) in chemotherapy-pretreated colorectal liver metastases (CRLM). Findings suggested that estimation of the future liver remnant function (eFLRF) by combining ^99mTc-Mebrofenin HBS^BSA predicted post-hepatectomy liver failure (PHLF) better than PBLS or HBS^BSA alone. PBLS seemed to measure other aspects of liver function or damage than HBS^BSA.