Skrifvars MB, et al. – This post hoc analysis was performed to test the hypothesis that erythropoietin (EPO) decreases mortality more in traumatic brain injury (TBI) patients with multiple trauma than in patients with TBI alone. The authors revealed that in TBI patients with a more severe extracranial injury, EPO administration was correlated with a potential differential improvement in 6–month mortality. These findings needed confirmation in future clinical and experimental studies.