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Erosive pustular dermatosis of the scalp: A multicentre study

Journal of the European Academy of Dermatology and Venereology Feb 14, 2020

Starace M, Iorizzo M, Trüeb RM, et al. - Considering that erosive pustular dermatosis of the scalp (EPDS) is characterized by crusted erosions or superficial ulcerations that result in scarring alopecia, researchers conducted a multicentre retrospective clinical study to identify the epidemiology, clinical presentation, diagnostic findings, treatment options and outcomes of this rare, but not to be ignored, disorder. Participants in the study were 56 individuals (29 women and 27 men, age range 18–95 years, mean 62.7 years) with a confirmed EPDS. According to results, mechanical/chemical trauma has been recorded in 28.6%, a previous infection in 10.7%, previous cryotherapy in 5.4% androgenetic alopecia in 48.2% and severe actinic damage in 25%. Trichoscopy demonstrated the absence of follicular ostia, tufted and broken hair, crusts, serous exudate, dilated vessels, pustules, and hyperkeratosis. Topical steroids, followed by the combination of topical steroids and topical tacrolimus, systemic steroids and topical tacrolimus, were the most prescribed therapy. The relatively high number of patients obtained enabled us to identify a better diagnostic approach using trichoscopy and a more effective therapeutic strategy with high-potency steroids or tacrolimus that should be considered first-line therapy.
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