Patelli F, Falleni M, Colombo L, et al. - In the present study, the researchers sought to examine morphologic and histochemical features of epiretinal fibrosis removed in an Argus II–implanted eye and to assess the Argus II function before and after the fibrosis removal, as well as to compare morphologic and functional data. The Argus II function was assessed during the follow-up before surgical removal and 1 month later. Findings suggested that fibrosis can develop between the Argus II and the retina with increasing diminished function. A pathogenesis based on an inflammatory process involved in a foreign body reaction with progressing connective tissue deposition leading to sclerosis was indicated by morphologic features of the removed fibrosis. For successful removal of fibrosis with reactivation of the Argus II function, adequate clinical follow-up is important.