Chunyan Li, et al. - In this retrospective study, researchers analyzed the demographic and characteristic distribution data of serious rural pediatric eye injuries in Wenzhou and Changsha, located in Zhejiang Province in East China and Hunan Province in Central China. Participants in the study were hospitalized pediatric patients aged < 18 years with eye injuries at the Eye Hospital of Wenzhou Medical University and Xiangya Hospital of Central South University from January 2008 to December 2017. A total of 1,125 children [467 children were admitted to the Eye Hospital of Wenzhou Medical University and 658 children were admitted to the Xiangya Hospital of Central South University], mean age was 7.0 ± 4.1 years, were hospitalized during the 10-year period. According to results, most eye injuries in hospitalized children in rural areas were penetrating and occurred between the ages of 3 and 8 years. A sharp object, particularly scissors, was the main cause of injury. In Wenzhou, eye injuries occurred mainly during the summer, and sharp object-related eye injuries accounted for the highest proportion. In Changsha, eye injuries occurred mainly in winter, and the highest proportion was due to firecracker- and fireworks-associated eye injury. Notably, regional features were linked to the variations in the characteristics of eye injuries in the two areas.