Foxwell DA, et al. - Researchers performed this prospective cohort study in a University Teaching Hospital (UK), to report the incidence, demographics as well as results of patients diagnosed with Acute Kidney Injury (AKI) in the Emergency Department (ED) (ED-AKI). Overall 20,421 adult patients visited the ED and underwent serum creatinine measurement. They compared incident ED-AKI patient episodes with a randomly picked cohort of non-AKI ED patients. A 24.4% in-patient mortality was noted in relation to ED-AKI, with the occurrence of 22.3% of deaths within 24-hours and 58% within 7-days. A 38.8% mortality was observed in relation to the progression of the admission AKI stage to a higher AKI stage vs 21.4% mortality observed in those who did not progress. ED-AKI was identified as an independent predictor of mortality. Mortality was predominantly in the early stages of hospital admission, but significant long-term morbidity and mortality were observed in those who survived to discharge.