Corcione S, et al. - A single-center retrospective study is performed to explore the association between epidemiology and risk factors for mortality in bloodstream infection by carbapenemase-producing K. pneumoniae (CP-Kp), ESBL-E, Candida and C. difficile infection (CDI). This information demonstrated that CDI, ESBL-E BSI and candidemia are more frequent in frail patients, admitted to internal medicine wards (IMW), with chronic comorbidities and broad exposure to antibiotic therapies, with the exception for CP-Kp BSI, still more common in the intensive care unit (ICU).