Karpouzas GA, Rezaeian P, Ormseth SR, et al. - This study attempted to explore epicardial adipose tissue volume (EATV) and its link to coronary atherosclerosis and plaque morphology in patients with rheumatoid arthritis (RA) and in age- and gender-matched controls. Researchers used computed tomography angiography to assess EATV and coronary plaque in 139 RA patients and 139 non-RA controls. They further computed odds ratios and 95% confidence intervals (95% CIs). The results showed that EATVs were correlated with greater plaque burden and presence of plaques with a noncalcified component and vulnerability features only in RA patients, despite similar EATVs in RA patients and controls. In RA, EAT may be more pathogenic and play a role in early-stage atherosclerosis. Its value as a biomarker of subclinical atherosclerosis and cardiovascular risk in RA needs future trials.