Gao S, et al. - Given that atherosclerosis can be accelerated by allergic asthma and eosinophils are known as the most essential effector cells in allergic asthma, researchers assessed the use of eosinophils in predicting coronary artery disease (CAD). They recruited 5,287 patients who underwent coronary angiography. Measurements of their biochemical parameters, including eosinophil count, were obtained and correlation with the severity of coronary artery stenosis, using the Gensini score system was assessed. Findings suggested a possible strong association of percentages of eosinophils in leukocytes with the subtype and severity of CAD, at least in patients undergoing coronary angiography. This indicates a possible role of eosinophil count as an accurate and independent biomarker to predict CAD severity and acute coronary arterial thrombotic events. Percentages of eosinophils in leukocytes added to traditional risk factors in predictive models for CAD severity or acute coronary arterial thrombotic event improved the predictive capabilities of those models, according to receiver-operating characteristic curve analysis.