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Environmental peanut exposure increases the risk of peanut sensitization in high-risk children

Clinical & Experimental Allergy May 18, 2018

Brough HA, et al. - Researchers determined the link between environmental peanut exposure (EPE) and school-age peanut sensitization in a population-based cohort. Using a conditional regression analysis, peanut-sensitized cases were compared against high-risk controls (matched for parental atopy) in an initial nested case-control analysis. Whole cohort analysis was performed to compare EPE against peanut sIgE sensitization at ages 4 and 8 years and against primary peanut sensitization at age 8 years. The probability of developing school-age peanut sensitization in atopic children (based on egg sensitization and parental atopy) appeared to be increased as a consequence of higher levels of environmental exposure to peanut in the first few months of life.
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