Kedir HM, Abyie AA, et al. - The results exhibited that ECA treatment is not an effective mechanism against gastrointestinal (GI) protection, and it is highly correlated with small bowel injury. So the coating does not decrease the risk of GI complications.

• Between April 10th to April 23rd, 2020, researchers conducted a systematic search of the literature in the PubMed electronic databases.

• They collected data from 6 published articles that reported on 15,621 participants.

• Furthermore, the reports were from 3 different countries. It was shown that enteric-coated aspirin (ECA) treatment was not an effective mechanism against GI protection.

• Compared with the impact of ECA used alone, ECA administration with omeprazole can hugely reduce the incidence of endoscopic GI damage.

• The findings revealed that even short-term administration of a low dose of ECA was significantly correlated with an apparent small bowel injury.