Liu MC, et al. - Researchers sought to assess the function of antigen presenting cells (APC) and T lymphocytes (TC) accumulating at sites of inflammation subsequent to segmental allergen challenge (SAC). According to findings, the recruitment of monocytes and dendritic cells was largely responsible for the marked increase in APC function for allergen-specific TC proliferation during allergic inflammation. An enhanced response in the lung TC population was noted, consistent with recruitment of allergen-specific T cells. The observations suggested that interactions between recruited APC and TC may occur as an early event promoting allergic airway inflammation.