Elsebaey MA, et al. - In 113 cirrhotic patients, researchers evaluated the safety and effectiveness of sclerotherapy vs cyanoacrylate injection for management of actively bleeding esophageal varices. Both of these therapies seem to have relatively favorable results based on this prospective single-center study, although cyanoacrylate injection might be superior to sclerotherapy for initial control of active bleeding. In patients with actively bleeding esophageal varices, both injection sclerotherapy and cyanoacrylate injection should be considered when band ligation is technically difficult. There were no significant differences between sclerotherapy and cyanoacrylate groups regarding rebleeding [defined as the occurrence of a new episode of hematemesis or melena that associated with hemodynamic instability or a drop in hemoglobin concentration more than 2 g% per day in a previously stable patient], complications, hospital stay or mortality rate.