Sang HM, et al. - Researchers sought to identify the correlation of endoscopic features with the histopathology of specimens of esophageal high-grade intraepithelial neoplasia attained by endoscopic submucosal dissection (ESD). From January 2010 to December 2015, they developed a retrospective study including 169 patients who underwent ESD and were diagnosed with esophageal high-grade intraepithelial neoplasia according to endoscopic forceps biopsy, Lugol staining, endoscopic ultrasonography, computed tomography, and Narrow-Band Imaging. As per findings, lesion size > 2 cm, depressed and excavated patterns, and ≤ 4 biopsy samples were noted to be independent risk factors for histological grade changes vs pre-endoscopic treatment diagnosis. Similarly, independent risk factors for non-curative resection included leukoplakia and no Lugol staining of lesions.