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Endometriosis does not impact live-birth rates in frozen embryo transfers of euploid blastocysts

Fertility and Sterility Sep 24, 2020

Bishop LA, Gunn J, Jahandideh S, et al. - In order to determine whether impaired endometrial receptivity explains the subfertility in patients with endometriosis, researchers conducted a retrospective cohort study comparing pregnancy and live-birth outcomes in women with endometriosis vs two control groups without suspected endometrial factors: noninfertile patients who underwent assisted reproduction to test embryos for a single-gene disorder and couples with isolated male factor infertility. In the analysis, 459 euploid frozen embryo transfer cycles among 328 unique patients were included. Findings did not clarify whether endometriosis primarily impacts in vitro fertilization outcomes via oocyte quality or the endometrium. Clinical pregnancy, pregnancy loss, or live-birth rates in patients with endometriosis did not differ from those noted with patients undergoing treatment for male factor infertility and noninfertile patients. 

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