Demiral I, et al. - The endometrial gene expressions of patients with recurrent implantation failure (RIF) and discover which genes may be involved in implantation failure were evaluated in this study. Using endometrial microarray gene expression to study RIF patients, researchers showed 607 differentially-expressed genes, involved in 40 functional pathways. The top 25 differentially-expressed genes (DEGs) exhibit 16 DEGs that were up-regulated and 9 down-regulated in RIF patients compared to control. Two genes, ACTB and WASF1, both up-regulated in patients with RIF, could be consistently used to discriminate RIF patients from control fertile patients.