Wetz AJ, et al. – This study entailed testing of the validity of a presumption that end–tidal control is superior to manually controlled minimal–flow anesthesia (0.5 l/min). Findings demonstrated that in comparison to manual control, end–tidal control displayed superiority in terms of setting and maintaining oxygen and anesthetic gas concentrations in a stable and rapid manner. Consequently, end–tidal control could effectively support the anesthetist.