Engel TW, et al. - In this prospective study involving cardiac arrest (CA) patients resuscitated in the emergency department (ED), end tidal CO₂ (ETCO₂) was compared with cerebral oximetry (CerOx) for return of spontaneous circulation (ROSC) prediction during both out of hospital (OHCA) and EDCAs. Researchers analyzed 176 patients: 66.7% were witnessed and 52.8% had bystander cardiopulmonary resuscitation. According to findings, return of spontaneous circulation in cardiac arrest could be efficiently predicted using both ETCO₂ and rSO₂. CerOx was identified as superior to ETCO₂ in predicting return of spontaneous circulation.