Aykut B, et al. – An analysis appraised the prognostic significance of EMX2 (Empty Spiracles Homeobox 2) expression in stage III colorectal adenocarcinoma. As per the outcomes, EMX2 was frequently down–regulated in human colorectal cancer, this down–regulation of EMX2 was a prognostic marker for disease–free and overall survival. Moreover, EMX2 seemed to represent a promising therapeutic target in colorectal cancer.