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Emulsion of olive oil and calcium hydroxide for the prevention of radiation dermatitis in hypofractionation post-mastectomy radiotherapy: A randomized controlled trial

Breast Care Feb 10, 2019

Chitapanarux I, et al. - Researchers assessed the efficacy of emulsion of olive oil and calcium hydroxide for preventing radiation dermatitis in 62 breast cancer patients who received hypofractionation post-mastectomy radiotherapy (PMRT). From the initiation of PMRT to 2 weeks post-radiotherapy, participants were randomized to receive a general skin care regimen with or without the addition of an emulsion of olive oil and calcium hydroxide twice a day. Assessments of adverse skin reactions and the Skindex-16 score were carried out. Findings revealed that superior preventive results were seen with the addition of an emulsion of olive oil and calcium hydroxide vs a general skin care regimen alone in patients undergoing hypofractionation PMRT. The benefits seen in the intervention group included delaying of skin toxicity, reduction in the severity of acute radiation dermatitis, and a better quality of life.
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