Kapur S, et al. - Between September 2015 and January 2016, a prospective audit of management of infants between 30 and 180 days attending the regional paediatric emergency department(ED) in Northern Ireland, within 4 days of receiving 4-component meningococcal B vaccine(4CMenB) was conducted. In this study, researchers observed that about 0.8% of the vaccinated population in the catchment area attended ED with symptoms occurring after primary vaccinations including 4CMenB. Infants with fever seemed to be at greater risk of serious bacterial infection(SBI), but infants with fever in the post-vaccination period may not have the same risk. They recommend further studies to inform national guidelines on investigation and management of fever in infants following vaccination with 4CMenB, possibly incorporating a less-invasive approach.