Andrade MMC, Carneiro VL, Galvão AA, et al. - Given that Toxoplasma gondii (T gondii) infection has been related to protection against allergy and autoimmune diseases, researchers determined how cytokine and antibody responses in atopic and nonatopic Brazilian people are influenced by T gondii infection. Findings revealed a significant negative link between high levels of anti-dust mite IgE and T gondii seropositivity. In Tg-positive atopic people vs Tg-negative atopic individuals, a mixed profile of Th1 and Th2 cytokines (IFN-γ, IL-12 and IL-5) which was induced by T gondii soluble tachyzoites antigen stimulation was reported. There was no link between T gondii infection and asthma. A hypothesis was formulated that the protective impact on atopy might be associated with the strong Th1 immune response to T gondii seen on the seropositive individuals. The link between atopy and T gondii infection in Brazilian people was inquired for the first time ever in this study, with an analysis of cellular immune responses.