Switlyk MD, et al. - In prostate cancer, researchers ascertained if phosphatase and tensin homolog (PTEN) expression correlated with clinicopathologic characteristics and multiparametric MRI findings. For this analysis, they involved 43 patients with prostate cancer who had radical prostatectomy. They evaluated pretreatment serum levels of prostate-specific antigen, disseminated tumor cell status, age, Gleason score, tumor size, extraprostatic extension (EPE), tumor location, and lymph node metastases. A weak but significant association was revealed on bead arrays between PTEN expression, EPE, and Gleason score. Gleason score and tumor size were negatively correlated with apparent diffusion coefficient. Findings suggested that DWI-derived ADC could be helpful in selecting patients with potentially aggressive tumor due to PTEN deficiency. Among DCE parameters, PTEN expression, and clinicopathologic characteristics, no association was seen.