Harun SN, et al. - Via cross-sectional analysis of data from the Australasian Cystic Fibrosis Bronchoalveolar Lavage study, researchers focused on the risk and explanatory factors of acquiring Aspergillus in children with cystic fibrosis (CF) by age 5 years. For the first P. aeruginosa positive culture and for the first Aspergillus positive culture, the median (IQR) age was 2.38 (1.32-3.79) years and 3.69 (1.68-4.74) years, respectively. Following first year of study entry, alterations in the risk of P. aeruginosa and Aspergillus events were evident with time. Risk for P. aeruginosa was lower following the completion P. aeruginosa eradication, but it increased for Aspergillus events. Increased risk of acquiring Aspergillus was reported in relation to completing P. aeruginosa eradication therapy and previous Aspergillus events in young children with CF.