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Helicobacter pylori-associated peptic ulcer disease: A retrospective analysis of post-treatment testing practices

Helicobacter Sep 28, 2018

Feder R, et al. – Guidelines recommend that patients with Helicobacter pylori-associated peptic ulcer disease (PUD) receive H. pylori eradication therapy followed by post-treatment testing to prove eradication. However, post-treatment testing rates are substandard, and barriers to testing are not well understood. Thus, researchers performed a retrospective cohort study of 152 patients with H. pylori-associated PUD to identify factors that may predict receipt of post-treatment testing. Study participants were diagnosed with H. pylori-associated PUD between 2007 and 2015 at a large tertiary medical center in the US, and received standard eradication therapy and ambulatory follow-up within 1 year. Logistic regression models were used to compare post-treatment rates in those diagnosed while outpatient vs in patient, patients with vs without endoscopy, and patients with vs without gastroenterology (GI) clinical follow-up. Researchers found that the rate of testing for eradication after treatment in was low. However, this was significantly improved in patients who had GI follow-up and whose diagnosis was made in the outpatient setting.

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