Rezapour M, et al. - Among adults with inflammatory bowel disease (IBD) hospitalized in the USA, researchers assessed the impact of Clostridium difficile co-infection (CDCI) on in-hospital outcomes. The 2007–2013 Nationwide Inpatient Sample was used to assess hospitalizations among US adults with Crohn’s disease (CD), ulcerative colitis (UC) and CDCI using ICD-9 coding. The findings from the present study suggested that CDCI was correlated with significantly greater in-hospital mortality and greater healthcare utilization among US adults with CD and UC related hospitalizations.