Mandurino-Mirizzi A, Kajana V, Cornara S, et al. - Among patients with ST-segment elevation myocardial infarction (STEMI) managed with primary percutaneous coronary intervention (pPCI), this inquiry was undertaken to examine the link between elevated serum uric acid (eSUA) and contrast associated-acute kidney injury (CA-AKI). At admission and 24, 48 and 72 hours post-pPCI, measurements of serum creatinine (Scr) were obtained. CA-AKI was defined as a rise of 25% (CA-AKI 25%) or 0.5 mg/dl (CA-AKI 0.5) of Scr concentration above the baseline following 48 hours post-contrast use. In the 3023 patients considered, more frequency of CA-AKI was identified in patients with eSUA vs patients with normal SUA concentrations, considering both CA-AKI definitions. Findings in this study population revealed a link of elevated serum uric acid with CA-AKI post-reperfusion.