El-Menyar A, et al. - Via this systematic review and meta-analysis, researchers investigated if raised levels of cardiac troponin increase the mortality risk in patients with acute pulmonary embolism (PE). They searched Cochrane Library, MEDLINE, PubMed, Scopus, Cochrane Central Register of Controlled Trials (CENTRAL), WHO International Clinical Trials Registry Platform, and Google Scholar databases to identify publications (2000–2018) that were retrospective, prospective, and randomized controlled trials (RCT) or quasi-RCT studies and evaluated the influence of elevated troponin vs normal levels on the outcomes of PE. All-cause mortality was the main outcome of interest. They identified a total of 1,825 references, of which, 46 analytical studies including 10,842 patients with PE were included and analyzed. As per the pooled analysis, a significant link of elevated troponin with higher mortality in patients with PE was found, irrespective of the troponin assay.