Sonoda H, Yamada T, Matsuda A, et al. - Researchers investigated if postoperative carcinoembryonic antigen (CEA) [post-CEA] increase might indicate a poor prognosis for stage II-III colorectal cancer (CRC) patients who had curative surgery. This study included 482 patients with pathological stage II-III CRC. To assess post-CEA concentrations, univariate and multivariate analyses were conducted. Findings demonstrated an independent link of post-surgical CEA elevation with a poor prognosis in stage II-III CRC. By addition of post-CEA concentrations to the IDEA (International Duration Evaluation of Adjuvant Chemotherapy) risk classification, a more dependable indicator may be obtained for the necessity for individualized surveillance and adjuvant chemotherapeutic strategies.