Argan O, et al. - The clinical correlates and predictive significance of vitamin B12 levels in stable systolic heart failure (HF) was examined in this analysis. For this investigation, 129 consecutive patients with HF and 50 control subjects were recruited. Researchers performed Cox proportional hazards regression analyses to determine the independent predictive determinants of mortality. It was observed that increased B12 in stable HF patients correlated with increased direct bilirubin due to right HF, indicating a cardiohepatic syndrome, however, neither B12 nor folic acid was independently linked with mortality.