Elevated high-sensitivity C-reactive protein combined with procalcitonin predicts high risk of contrast-induced nephropathy after percutaneous coronary intervention
BMC Cardiovascular Disorders Jul 02, 2019
Gu G, et al. - Researchers assessed if high-sensitivity C-reactive protein (hs-CRP) combined with procalcitonin could predict contrast-induced nephropathy (CIN) post-percutaneous coronary intervention (PCI) in this prospective analysis. Participants were consecutively enrolled patients (n = 343) undergoing PCI. Adequate hydration prior to PCI and 20 mg furosemide following the procedure was received by patients. Rise in hsCRP and procalcitonin (inflammatory biomarkers) before PCI conferred risk for postoperative CIN. Compared to either hsCRP or procalcitonin alone, the combination of hsCRP and procalcitonin was shown to provide a better prediction of CIN post- PCI in this study.
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