Barré T, Protopopescu C, Bani-Sadr F, et al. - Experts aspired to explore if elevated fatty liver index (FLI), a noninvasive steatosis biomarker, (≥ 60) was correlated with all-cause mortality utilizing a Cox proportional hazards model for mortality from all causes, with data from the French National Agency for Research on Aids and Viral Hepatitis CO13 HEPAVIH cohort (983 individuals, 4,432 visits). In this large cohort study, representative of HIV– hepatitis C virus (HCV)-coinfected French individuals in care, the authors discovered that an elevated FLI (≥ 60) is a risk factor for all-cause mortality in HIV–HCV-coinfected individuals independently of liver fibrosis and HCV cure. Such results are supporting the more systematic use of noninvasive steatosis biomarkers to help identify coinfected individuals with higher mortality risk in the present era of nearly 100% HCV cure levels thanks to direct-acting antivirals.