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Elevated diastolic wall shear stress in regurgitant semilunar valvular lesions

Journal of Magnetic Resonance Imaging Feb 07, 2019

Rizk J, et al. - In this retrospective data analysis, researchers examined diastolic wall shear stress (WSS) in aortic and pulmonary regurgitation. The study sample consisted of 30 tetralogy of Fallot patients, 19 bicuspid aortic valve patients, 11 healthy volunteers. Compared to controls, WSS was higher in pulmonary regurgitation (PR) and aortic regurgitation (AR) along the entire cardiac cycle. in AR and PR, investigators found that higher diastolic WSS is a component of the altered flow hemodynamics, which could offer more understanding into the pathophysiological part WSS plays in vascular remodeling in AR and PR.

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