Jackson SS, et al. – Researchers here performed a multicenter retrospective cohort study of patients undergoing surgical procedures at 28 US hospitals and developed a well–performing risk adjustment model for surgical site infections (SSIs) using electronically available comorbidities. They strongly recommend considering comorbidity–based risk adjustment by the Centers for Disease Control and Prevention (CDC) and Centers for Medicare and Medicaid Services (CMS) to adequately compare SSI rates across hospitals.