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Elective neck dissection in patients with radio-recurrent and radio-residual squamous cell carcinoma of the larynx undergoing salvage total laryngectomy: Systematic review and meta-analysis

Head & Neck Aug 14, 2019

Lin DJ, et al. - In this systematic review and meta-analysis involving 1,141 patients, researchers ascertained if elective neck dissection (END) is indicated during salvage laryngectomy. Patients were identified from 17 studies. Findings revealed that there was no significant difference in 5-year disease-free survival and overall survival between END vs observation. Individual studies in supraglottic and locally advanced tumors trended towards improved survival with END. When deciding on END in salvage laryngectomy, these factors should be considered.
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