Aydin ME, Ahiskalioglu A, Ates I, et al. - This prospective, randomized, double-blind study is done with 48 adult patients undergoing cardiac surgery with median sternotomy, to determine how transversus thoracic muscle plane block (TTMPB) impacts opioid consumption after surgery in these patients. Patients were randomized to receive preoperative ultrasound-guided TTMPB with either 20 mL of 0.25% bupivacaine or saline bilaterally. The 2 groups were given postoperative analgesia, via intravenous route, 4 times a day with 1000 mg of paracetamol and patient-controlled analgesia with fentanyl. Overall, in patients receiving cardiac surgery, effective analgesia was achieved with a single preoperative TTMPB, and this approach also afforded reduced opioid needs in this patient populace.